BDBM133680 US8846711, 24::US9051321, 24

SMILES CC(=O)Nc1ccc(\C=C\C(=O)N2CC(C2)OCc2ccncc2)cn1

InChI Key InChIKey=DWDZGSBLDPOJOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133680   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Fab Pharma

US Patent
LigandPNGBDBM133680(US8846711, 24 | US9051321, 24)
Affinity DataIC50: 260nMpH: 6.5 T: 2°CAssay Description:Compound inhibitory activity of FabI enzyme is measured in vitro by the IC5 so determination using a fluorescence based assay.The protein FabI from S...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Fab Pharma

US Patent
LigandPNGBDBM133680(US8846711, 24 | US9051321, 24)
Affinity DataIC50: 260nMpH: 6.5 T: 2°CAssay Description:The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent