BDBM13316 1-Methyl-1H-imidazole-4-sulfonic Acid Biphenyl-4-ylmethyl-{2-[(4-cyanophenyl)-(3-methyl-3H-imidazol-4-ylmethyl)amino]-ethyl}amide::N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino]ethyl}-1-methyl-N-[(4-phenylphenyl)methyl]-1H-imidazole-4-sulfonamide::Sulfonamide 12ag

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(cc1)C#N)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=MUGOBVVTADQYDA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 13316   

TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Yale University

LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13316(N-{2-[(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed