BDBM132275 US8841312, 17

SMILES C1CN(CCN1)c1ccc(Nc2ncc3c(n2)n(-c2ccccc2)c2cnccc32)cc1

InChI Key InChIKey=NMGQIPHNZLRCPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132275   

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132275(US8841312, 17)
Affinity DataIC50: 0.320nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandPNGBDBM132275(US8841312, 17)
Affinity DataIC50: 0.360nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails
US Patent