BDBM13105 CGS 27023A Analog 33::N-hydroxy-2-[(4-methoxybenzene)[(4-methoxyphenyl)methyl]sulfonamido]acetamide

SMILES COc1ccc(CN(CC(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=FVEJQZRUPDCJKK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13105   

TargetBone morphogenetic protein 1(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM13105(N-hydroxy-2-[(4-methoxybenzene)[(4-methoxyphenyl)m...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMeprin A subunit beta(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM13105(N-hydroxy-2-[(4-methoxybenzene)[(4-methoxyphenyl)m...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM13105(N-hydroxy-2-[(4-methoxybenzene)[(4-methoxyphenyl)m...)
Affinity DataKi:  104nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed