BDBM130869 US8829199, 137

SMILES COCCNc1cccc2[nH]c(cc12)C(=O)c1cnn(c1N)-c1ccc2[nH]c(C)nc2c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130869   

TargetFibroblast growth factor receptor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130869(US8829199, 137)
Affinity DataIC50: 6.40nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130869(US8829199, 137)
Affinity DataIC50: 19nMAssay Description:The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130869(US8829199, 137)
Affinity DataIC50: 26nMAssay Description:The FGFR3-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent