BDBM130866 BDBM50197685::US8829199, 132
SMILES Cc1nc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccc(CN4CCOCC4)cc3[nH]2)c1N
InChI Key
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 130866
Affinity DataIC50: 1.40nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:The FGFR3-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR1 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as reduction in channel currents at -80 mV holding potential by automated whole-cell patch cl...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human KDR by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human FGFR2 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human FGFR4 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human FGFR3 by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:The FGFR1 inhibitory activities of compounds were measured based on their activity to inhibit phosphorylation of the biotinylated peptide (EGPWLEEEEE...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:The FGFR2 inhibitory activities of compounds listed in Tables 1-1 to 1-5 were measured based on their activity to inhibit phosphorylation of the biot...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:The FGFR3 inhibitory activities of compounds listed in Tables 1-1 to 1-5 were measured based on their activity to inhibit phosphorylation of the biot...More data for this Ligand-Target Pair