BDBM130860 US8829199, 115

SMILES Cc6nc5cc(n4ncc(C(=O)c3cc2cc(CN1CCC(F)CC1)ccc2[nH]3)c4N)ccc5[nH]6

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130860   

TargetFibroblast growth factor receptor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130860(US8829199, 115)
Affinity DataIC50: 0.670nMAssay Description:The FGFR1-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130860(US8829199, 115)
Affinity DataIC50: 8.5nMAssay Description:The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM130860(US8829199, 115)
Affinity DataIC50: 30nMAssay Description:The FGFR3-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent