BDBM130367 US8822534, Example 11-14

SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(O)no1

InChI Key InChIKey=GUGWWNSCVAKENU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130367   

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM130367(US8822534, Example 11-14)
Affinity DataIC50: 0.0700nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
Go to US Patent