BDBM12892 (5S)-N-[(1S,2R)-3-[[(Benzo[1,3]dioxole-5-sulfonyl)](isobutyl)-amino]-1-benzyl-2-hydroxypropyl]-3-(3,4-difluorophenyl)-2-oxooxazolidine-5-carboxamide::(5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]-3-(3,4-difluorophenyl)-2-oxo-1,3-oxazolidine-5-carboxamide::N-Aryl-oxazolidinone-5-carboxamide Analogue 26c

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1ccc(F)c(F)c1)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=NMHTYOAWRSWRPT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12892   

TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School

LigandPNGBDBM12892((5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methyl...)
Affinity DataKi:  0.0850nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Umbi

Curated by ChEMBL
LigandPNGBDBM12892((5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methyl...)
Affinity DataKi:  0.0850nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Umbi

Curated by ChEMBL
LigandPNGBDBM12892((5S)-N-[(2S,3R)-4-[2H-1,3-benzodioxole-5-(2-methyl...)
Affinity DataKi:  0.0851nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed