BDBM128288 US8796295, Table 2: Compound: 12

SMILES Fc1cc(Oc2cncnc2)cc(c1)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=XBWJPFZNCGVCJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128288   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50: 813nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM128288(US8796295, Table 2: Compound: 12)
Affinity DataIC50: 1.07E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent