BDBM128279 US8796295, Table 2: Compound: 3

SMILES Fc1cccc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)n1

InChI Key InChIKey=FCGGFIQFAJSREN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128279   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50: 6.90nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM128279(US8796295, Table 2: Compound: 3)
Affinity DataIC50: 9.30nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent