BDBM12827 (1R,2S)-2-[2-(5-carbamimidoyl-1-benzothiophen-3-yl)-3-phenylpropanamido]cyclohexane-1-carboxylic acid; 2,2,2-trifluoroacetic acid::5-Amidinobenzo[b]thiophene 38::cis-racemic

SMILES NC(=N)c1ccc2scc(C(Cc3ccccc3)C(=O)N[C@H]3CCCC[C@H]3C(O)=O)c2c1

InChI Key InChIKey=QSCIZBQDANXSKY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12827   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12827((1R,2S)-2-[2-(5-carbamimidoyl-1-benzothiophen-3-yl...)
Affinity DataKi:  200nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12827((1R,2S)-2-[2-(5-carbamimidoyl-1-benzothiophen-3-yl...)
Affinity DataKi:  3.50E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed