BDBM127999 US8796310, 22F

SMILES CONC(=O)c1ccc2c(CCC[C@]2(O)c2ncc(s2)-c2cc(C)cc(Nc3cc(ccn3)C(F)(F)F)n2)c1

InChI Key InChIKey=MLBVUHDKFGVEEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127999   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM127999(US8796310, 22F)
Affinity DataIC50: 0.740nMpH: 7.5Assay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Cama Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
Go to US Patent