BDBM127938 US8796304, 2-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)sulfanylmethyl]-5H-imidazo[2,1-a]isoindole

SMILES Cc1cc(C)n2nc(SCc3cn4Cc5ccccc5-c4n3)nc2n1

InChI Key InChIKey=DPACRMHHSHLFDD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127938   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
H. Lundbeck

US Patent

LigandBDBM127938(US8796304, 2-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]...)Copy SMILESCopy InChI

Affinity DataIC50: 260nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/22/2014
Entry Details
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