BDBM127927 US8796304, 2-[2-(5,8-Dimethyl-7-oxy-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-5H-imidazo[2,1-a]isoindole::US9062060, Table 1, Compound 8

SMILES CC1N(O)C=C(C)n2nc(CCc3cn4Cc5ccccc5-c4n3)nc12

InChI Key InChIKey=RBZJEIPPAPHTSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127927   

LigandPNGBDBM127927(US8796304, 2-[2-(5,8-Dimethyl-7-oxy-[1,2,4]triazol...)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM127927(US8796304, 2-[2-(5,8-Dimethyl-7-oxy-[1,2,4]triazol...)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In DepthDetails
US Patent