BDBM127923 US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-vinyl]-5H-imidazo[2,1-a]isoindole::US9062060, Table 1, Compound 4

SMILES Cc1cnc(C)c2nc(C=Cc3cn4Cc5ccccc5-c4n3)nn12

InChI Key InChIKey=UXSSEAFAQUPALG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127923   

LigandPNGBDBM127923(US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 4.40nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM127923(US8796304, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 4.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In DepthDetails
US Patent