BDBM127330 US8791257, 129

SMILES COc1cc(ccn1)-c1cc(C(=O)N[C@H]2CC[C@@H](CC2)C(O)=O)c2c(N)ncnn12

InChI Key InChIKey=PUCDZZSVDMHUGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127330   

TargetCasein kinase II subunit alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM127330(US8791257, 129)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha'(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM127330(US8791257, 129)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
Go to US Patent