BDBM126487 US8778951, 297

SMILES CC1(C)CC(CNc2ccc(Cl)c(n2)-c2cc(N[C@H]3CC[C@H](O)CC3)ncc2Cl)CCO1

InChI Key InChIKey=FVWUIZMDTDYWLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126487   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Novartis

US Patent
LigandPNGBDBM126487(US8778951, 297)
Affinity DataIC50: 0.00100nMAssay Description:Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
Go to US Patent