BDBM126172 US8778957, 19

SMILES O=C1COc2ccccc2N1Cc1ccc2cc3C[C@]4(CNc5ncccc45)Cc3cc2n1

InChI Key InChIKey=NHKORSPDGIRXHE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126172   

TargetCalcitonin gene-related peptide 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126172(US8778957, 19)
Affinity DataKi:  2.90nM ΔG°:  -11.6kcal/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126172(US8778957, 19)
Affinity DataKi:  4.20nM ΔG°:  -11.4kcal/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In DepthDetails
US Patent