BDBM125465 US8772480, 320

SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)(O)C(F)(F)F)cn1

InChI Key InChIKey=AMLSTGMUISSLPX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 125465   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

US Patent
LigandPNGBDBM125465(US8772480, 320)
Affinity DataIC50: 263nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent

LigandPNGBDBM125465(US8772480, 320)
Affinity DataKi:  124nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent