BDBM124970 US8765747, 2

SMILES CCN1CCN(Cc2ccc(NC(=O)c3cccc(c3)-c3ccc4nc(NC(=O)C5CC5)sc4n3)cc2C(F)(F)F)CC1

InChI Key InChIKey=VTWWRKFUHCSCEW-UHFFFAOYSA-N

Data  21 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 124970   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  2.30nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetVascular endothelial growth factor receptor 2(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  58nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetAngiopoietin-1 receptor(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  57nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  5.60nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetPlatelet-derived growth factor receptor beta(Rat)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  1.80nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetPlatelet-derived growth factor receptor alpha(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  7.70nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetMitogen-activated protein kinase 12(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  100nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetSerine/threonine-protein kinase 10(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  9.5nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetMast/stem cell growth factor receptor Kit(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  2.90nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetHomeodomain-interacting protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  34nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetVascular endothelial growth factor receptor 3(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  31nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetTyrosine-protein kinase ABL1(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  3.30nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetVascular endothelial growth factor receptor 1(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  74nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetEpithelial discoidin domain-containing receptor 1(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  3.40nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetCyclin-dependent kinase 7(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  13nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetCyclin-dependent kinase 5(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  150nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetCyclin-dependent kinase 3(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  250nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetCyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  840nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetCyclin-dependent kinase 11B(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  32nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetSerine/threonine-protein kinase B-raf(Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  36nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Dana-Farber Cancer Institute

US Patent

LigandBDBM124970(US8765747, 2)Copy SMILESCopy InChI

Affinity DataKd:  1.20nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails
Copy BDB DOIUS Patent

Copy reaction URL