BDBM124090 US8754089, 4-amino-6-((1-(3-(3,5-difluorophenyl)-6-fluoro-1-methyl-4-oxo-1,4-dihydro-2-quinolinyl)ethyl)amino)-5-pyrimidinecarbonitrile

SMILES CC(Nc1ncnc(N)c1C#N)c1c(-c2cc(F)cc(F)c2)c(=O)c2cc(F)ccc2n1C

InChI Key InChIKey=YIHROKLLMDXLSC-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124090   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen

US Patent

LigandBDBM124090(US8754089, 4-amino-6-((1-(3-(3,5-difluorophenyl)-6...)Copy SMILESCopy InChI

Affinity DataKi:  33nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2014
Entry Details
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