BDBM123892 US8754113, I-2-196

SMILES Brc1cccc2sc(Cc3nnc(CC(=O)NCC#N)o3)nc12

InChI Key InChIKey=QAVOTORXYKURIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123892   

TargetEndothelial lipase(Human)
Shionogi

US Patent
LigandPNGBDBM123892(US8754113, I-2-196)
Affinity DataIC50: 36nMT: 2°CAssay Description:After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent