BDBM123879 US8748418, 24

SMILES CC1(C)OCC(N)=N[C@](C)(c2cc(Nc3cccnc3)ccc2F)C1(F)F

InChI Key InChIKey=XOQWCIWXRUAODU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123879   

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM123879(US8748418, 24)
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM123879(US8748418, 24)
Affinity DataIC50: 940nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In DepthDetails
US Patent