BDBM123274 US8742110, 5-10

SMILES CC1(C)CCOc2ccc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cc12

InChI Key InChIKey=DKWWEMHIIBBYKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 123274   

TargetSomatostatin receptor type 5(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM123274(US8742110, 5-10)
Affinity DataIC50: 1.54nMpH: 7.8Assay Description:SSTR5 binding assays can be performed by labeling somatostatin and determining the ability of a compound to inhibit somatostatin binding. (Poitout et...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSomatostatin receptor type 5(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM123274(US8742110, 5-10)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM123274(US8742110, 5-10)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM123274(US8742110, 5-10)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed