BDBM12179 (2S)-1-{[(2S,4S)-4-(2,3-dihydro-1H-isoindol-2-ylcarbonyl)-5,5-dimethylpyrrolidin-2-yl]carbonyl}pyrrolidine-2-carbonitrile::pyrrolidine-2,4-dicarboxylic acid amide 11b

SMILES CC1(C)N[C@@H](C[C@@H]1C(=O)N1Cc2ccccc2C1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=QEYHDPDDWVGRLP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12179   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM12179((2S)-1-{[(2S,4S)-4-(2,3-dihydro-1H-isoindol-2-ylca...)
Affinity DataIC50: 984nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM12179((2S)-1-{[(2S,4S)-4-(2,3-dihydro-1H-isoindol-2-ylca...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM12179((2S)-1-{[(2S,4S)-4-(2,3-dihydro-1H-isoindol-2-ylca...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

LigandPNGBDBM12179((2S)-1-{[(2S,4S)-4-(2,3-dihydro-1H-isoindol-2-ylca...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed