BDBM12170 5,6-dichloro-2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbonyl)pyrrolidin-3-yl]carbonyl}-2,3-dihydro-1H-isoindole::pyrrolidine-2,4-dicarboxylic acid amide 8f

SMILES Clc1cc2CN(Cc2cc1Cl)C(=O)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1

InChI Key InChIKey=XDUYJOAVSBIXIG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12170   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM12170(5,6-dichloro-2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50: 144nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM12170(5,6-dichloro-2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50: 1.22E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM12170(5,6-dichloro-2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

LigandPNGBDBM12170(5,6-dichloro-2-{[(3S,5S)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50: 5.13E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed