BDBM121143 US8722896, (+/-)-2-Methyl-3-((2- hydroxybenzyl)methylamino)-N- (9-chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpropanamide

SMILES CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)C(C)CNCc1cccc(O)c1

InChI Key InChIKey=HCMJCMYVOXIEMD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 121143   

TargetProkineticin receptor 2(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121143(US8722896, (+/-)-2-Methyl-3-((2- hydroxybenzyl)met...)
Affinity DataKi:  1.62nM ΔG°:  -12.5kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProkineticin receptor 2(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121143(US8722896, (+/-)-2-Methyl-3-((2- hydroxybenzyl)met...)
Affinity DataKi:  1.77nM ΔG°:  -12.4kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProkineticin receptor 1(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121143(US8722896, (+/-)-2-Methyl-3-((2- hydroxybenzyl)met...)
Affinity DataKi:  7.80nM ΔG°:  -11.5kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProkineticin receptor 1(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121143(US8722896, (+/-)-2-Methyl-3-((2- hydroxybenzyl)met...)
Affinity DataKi:  23.5nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent