BDBM121107 US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-chloro-3,4-dihydro-2H-1,5- benzodioxepin-7-ylmethyl)-N- isobutylpyrrolidine-3- carboxamide

SMILES CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)[C@@H]1CCN(Cc2cccc3CCNc23)C1

InChI Key InChIKey=VUZXMDAJKTULPG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121107   

TargetProkineticin receptor 2(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121107(US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-c...)
Affinity DataKi:  2.87nM ΔG°:  -12.1kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProkineticin receptor 1(Chinese hamster)
The Regents of The University of California

US Patent
LigandPNGBDBM121107(US8722896, (-)-(3R)-1-(Indolin-7-ylmethyl)- N-(9-c...)
Affinity DataKi:  17.8nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails
US Patent