BDBM120944 US8716285, 1

SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1ccc(F)cc1

InChI Key InChIKey=ZDMFHFPYBPYLCX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120944   

TargetHistone deacetylase 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM120944(US8716285, 1)
Affinity DataIC50: 2.68E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM120944(US8716285, 1)
Affinity DataEC50:  1.25E+4nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed