BDBM120944 US8716285, 1
SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1ccc(F)cc1
InChI Key InChIKey=ZDMFHFPYBPYLCX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 120944
Affinity DataIC50: 2.68E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Roche Pharmaceutical Research and Early Development
Curated by ChEMBL
Affinity DataEC50: 1.25E+4nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair