BDBM120913 US8716287, 46

SMILES CC(C)Oc1cc(CCNCc2ccc(F)cc2)c(Cl)cc1NC(=O)Nc1cnc(cn1)C#N

InChI Key InChIKey=RJTCZWWQMKFXNJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120913   

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent

LigandBDBM120913(US8716287, 46)Copy SMILESCopy InChI

Affinity DataIC50: 0.320nMpH: 7.5Assay Description:The compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set out below. Reaction Buffer: Base R...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/20/2014
Entry Details
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