BDBM120897 US8716287, 30

SMILES COc1cc(CCNCc2ccc(F)cc2F)ccc1NC(=O)Nc1cnc(cn1)C#N

InChI Key InChIKey=NOEAMTIELJQYED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120897   

TargetSerine/threonine-protein kinase Chk1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM120897(US8716287, 30)
Affinity DataIC50: 6.40nMpH: 7.5Assay Description:The compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set out below. Reaction Buffer: Base R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent