BDBM120853 US8716478, D239::US9499570, D239

SMILES OB1OCc2cc(Oc3nc(OCCOC4CC4)c(cc3Cl)C#N)ccc12

InChI Key InChIKey=JXQLQPODTZFKHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120853   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM120853(US8716478, D239 | US9499570, D239)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM120853(US8716478, D239 | US9499570, D239)
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent