BDBM120812 US8716482, 15

SMILES CS(=O)(=O)N1C[C@H](C[C@H](N)C1c1cc(F)ccc1F)N1Cc2cn(nc2C1)S(C)(=O)=O

InChI Key InChIKey=SFYWPGQOOTZGPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120812   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM120812(US8716482, 15)
Affinity DataIC50: 53.3nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent