BDBM120802 US8716482, 5

SMILES CN1C[C@@H](C[C@H](N)C1c1cc(F)c(F)cc1F)N1Cc2cn(nc2C1)S(C)(=O)=O

InChI Key InChIKey=PXWNVWRPDHAUBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120802   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM120802(US8716482, 5)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent