BDBM117269 US8653087, I-56

SMILES CN1CCC(CC1)N1CCN(CC1)c1nc(N)c2ncnc(Nc3cc(ccc3C)C(=O)Nc3cccc(c3)C(F)(F)F)c2n1

InChI Key InChIKey=SYBOGNVDCRAONH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117269   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117269(US8653087, I-56)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
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US Patent