BDBM117229 US8653087, I-16

SMILES COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4c(N)nc(nc34)N3CCN(CC4CCN(C)CC4)CC3)c2)cc1C(F)(F)F

InChI Key InChIKey=FXKHIHYOTSLSAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117229   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117229(US8653087, I-16)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
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US Patent