BDBM11719 (2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-methyl-4-oxobutan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile::(2S)-Cyanopyrrolidine analogue 21d::(2S)-cyanopyrrolidine 4::2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,3-dihydroisoindole

SMILES CC(C)(CC(=O)N1Cc2ccccc2C1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=BXAZNJCLCXBVJT-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 11719   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 15nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 15nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 15nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11719((2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed