BDBM117040 US8664236, A20::US9238651, A20

SMILES CCN(c1nncs1)c1cc(nc(N)n1)-c1c[nH]c2ncc(cc12)-c1cnn(C)c1

InChI Key InChIKey=NGVDOVMTTQHYBC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 117040   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM117040(US8664236, A20 | US9238651, A20)
Affinity DataIC50: 155nMAssay Description:The compound inhibits the target protein in the enzymatic PDK1 inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM117040(US8664236, A20 | US9238651, A20)
Affinity DataIC50: 155nMT: 2°CAssay Description:The experimental batches are carried out in a flashplate system with 384 wells/microtitration plate.In each case, the PDK1 sample His6-PDK1(Δ1-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM117040(US8664236, A20 | US9238651, A20)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The cellular assay for the determination of the PDK1 kinase activity is carried out as a Luminex assay in the 96-well format. PC3 cells are sown at 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent