BDBM11676 (2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,2,4-oxadiazol-5-yl]-4-cyclopropyl-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-aminium; 2,2,2-trifluoroacetate::alpha-amino acid pyrrolidide 38::oxadiazole based amide

SMILES CS(=O)(=O)c1ccc(-c2noc(n2)[C@@H](CC2CC2)[C@H]([NH3+])C(=O)N2CC[C@H](F)C2)c(Cl)c1

InChI Key InChIKey=AMJXVSDUENPVDD-UHFFFAOYSA-O

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11676   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 13nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 1.70E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DPP4 expressed in insect cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11676((2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant QPP expressed in baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed