BDBM11659 N-(4-{5-[(2S,3S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butan-2-yl]-1,2,4-oxadiazol-3-yl}phenyl)methanesulfonamide::alpha-amino acid pyrrolidide 21::oxadiazole based amide

SMILES C[C@@H]([C@H](N)C(=O)N1CCCC1)c1nc(no1)-c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=WGWUUVBDHZLMNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11659   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11659(N-(4-{5-[(2S,3S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 520nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11659(N-(4-{5-[(2S,3S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 5.40E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11659(N-(4-{5-[(2S,3S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11659(N-(4-{5-[(2S,3S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed