BDBM11622 β-CA inhibitor, 1::2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,5-disulfonamide::5-(4-Amino-3-chlorobenzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide::aminobenzolamide 17c

SMILES Nc1ccc(cc1Cl)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=CYGCWJCVIJAEOL-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11622   

TargetCarbonic anhydrase 2(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  0.600nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  2.40nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  46nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  170nM ΔG°:  -9.23kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  290nM ΔG°:  -8.91kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit�� Degli Studi Di Firenze

LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  450nM ΔG°:  -8.65kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed