BDBM114291 8-(3,4,5-trihydroxy-6-keto-xanthen-9-yl)-1-naphthoic acid::8-(3,4,5-trihydroxy-6-oxo-9-xanthenyl)-1-naphthalenecarboxylic acid::8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-1-carboxylic acid::8-[3,4,5-tris(oxidanyl)-6-oxidanylidene-xanthen-9-yl]naphthalene-1-carboxylic acid::MLS002706942::SMR001574339::cid_274108

SMILES OC(=O)c1cccc2cccc(-c3c4ccc(O)c(O)c4oc4c(O)c(=O)ccc34)c12

InChI Key InChIKey=NYLLADZYPUKUTH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 114291   

Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114291(8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-...)
Affinity DataIC50: 1.22E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114291(8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-...)
Affinity DataIC50: 1.22E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114291(8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-...)
Affinity DataIC50: 348nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114291(8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-...)
Affinity DataIC50: 369nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay
LigandPNGBDBM114291(8-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)naphthalene-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of G-protein beta1gamma2 (unknown origin) by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed