BDBM11351 Hydroxamate 32::N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pentafluorobenzene)sulfonamido}acetamide

SMILES ONC(=O)CN(Cc1ccccc1N(=O)=O)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=ROMGJVVZNVJOPW-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11351   

TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  1nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  1.30nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  1.40nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  6nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  6nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  49nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  74nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11351(N-hydroxy-2-{[(2-nitrophenyl)methyl](2,3,4,5,6-pen...)
Affinity DataKi:  127nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed