BDBM113224 US8633212, 2

SMILES COC1CCC2(Cc3ccc(cc3C22ON(C)C(N)=N2)-c2cc(Cl)cc(c2)C#N)CC1

InChI Key InChIKey=UUXWNRAWHSOACD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113224   

TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113224(US8633212, 2)
Affinity DataIC50: 3.5nMpH: 4.5 T: 2°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity. The assay was performed at room temperature in 96-well...More data for this Ligand-Target Pair
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US Patent