BDBM11287 N-(4-chlorophenyl)-2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)sulfanyl]propanamide::acs.jmedchem.1c00409_ST.796::pyrimidinone-containing compound 24

SMILES CC(Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=DGNRVGPZXZKQQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11287   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11287(N-(4-chlorophenyl)-2-[(5-cyano-6-oxo-4-phenyl-1,6-...)
Affinity DataIC50: 3.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11287(N-(4-chlorophenyl)-2-[(5-cyano-6-oxo-4-phenyl-1,6-...)
Affinity DataIC50: 3.00E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed