BDBM11276 2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-acetylphenyl)acetamide::acs.jmedchem.1c00409_ST.717::pyrimidinone-containing compound 13

SMILES COc1cccc(c1)-c1nc(SCC(=O)Nc2ccc(cc2)C(C)=O)[nH]c(=O)c1C#N

InChI Key InChIKey=PWZKDBYJLZTANB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11276   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11276(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50: 6.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11276(2-{[5-cyano-4-(3-methoxyphenyl)-6-oxo-1,6-dihydrop...)
Affinity DataIC50: 6.00E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed