BDBM11274 N-[4-(propan-2-yl)phenyl]-2-{[4-(thiophen-2-yl)pyrimidin-2-yl]sulfanyl}acetamide::acs.jmedchem.1c00409_ST.685::pyrimidine-containing compound 11

SMILES CC(C)c1ccc(NC(=O)CSc2nccc(n2)-c2cccs2)cc1

InChI Key InChIKey=UUBHDKPSKIQBFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11274   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11274(N-[4-(propan-2-yl)phenyl]-2-{[4-(thiophen-2-yl)pyr...)
Affinity DataIC50: 4.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11274(N-[4-(propan-2-yl)phenyl]-2-{[4-(thiophen-2-yl)pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed