BDBM111859 US8623906, JF040::US9174969, JF040

SMILES FC(F)(F)c1ccccc1NC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1cccc(Cl)c1

InChI Key InChIKey=BMYMTEKSTSNICN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111859   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM111859(US8623906, JF040 | US9174969, JF040)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM111859(US8623906, JF040 | US9174969, JF040)
Affinity DataIC50: 9.00E+3nMAssay Description:IC50 values for indoline Shp2 inhibitors of the present invention, as determined by in vitro phosphotyrosine phosphatase activity (DiFMUP) assay. More data for this Ligand-Target Pair
In DepthDetails
US Patent