BDBM111589 US8618098, III-1::US8822457, III-1

SMILES CN(C)c1ccc2c(cnn(-c3cccc(-c4cc(Nc5ccc(cn5)C(=O)N5CCOCC5)c(=O)n(C)c4)c3C)c2=O)c1

InChI Key InChIKey=HOTPGCYVRVQNGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111589   

TargetTyrosine-protein kinase BTK(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM111589(US8822457, III-1 | US8618098, III-1)
Affinity DataIC50: 124nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent